Nanoscale Shape-Dependent Histone Modifications

<p>Recent observations suggest a role for complex nanoscale particulate shape in regulation of specific immune-related cellular and in vivo processes. We suspect that cellular recognition of nanostructure architecture could involve non-molecular inputs, including cellular transduction of nanoscale spatially resolved stresses induced by complex shape. Here we report nanoscale shape-dependent control of the cellular epigenome. ChIP-Seq sequencing datasets are provided.</p>