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X-Ray Structures of Target-Ligand Complexes Containing Compounds with Assay Interference Potential

<p>A total of 2755 crystallographic complexes&nbsp;with ligands containing PAINS-defining substructures were extracted from the Protein Data Bank (PDB). PDB identifiers of these structures are made available together with the the corresponding PDB_PAINS&nbsp;(component identifier, aromatic nonstereo SMILES, PAINS class).&nbsp;</p>

ShareScore

40/100

Overall dataset sharing score

Score breakdown

These five areas show where the dataset supports — or may limit — practical reuse.

Stewardship
8
Harmonization
4
Access
20
Reuse readiness
8
Engagement
0

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