Genome-wide association summary statistics for G4 and G6

<p>This repository contains GWAS summary statistics for G4 (g4_GWAS_Sumstats_Cleaned.txt) and G6 (g6_GWAS_Sumstats_Cleaned.txt), which are part of the paper titled "Dynamics of cognitive variability with age and its genetic underpinning in NIHR BioResource Genes and Cognition cohort participants".</p> <p>For methodological details check the paper at: <span><a href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.nature.com%2Farticles%2Fs41591-024-02960-5&amp;data=05%7C02%7Cshafiqur.rahman%40mrc-bsu.cam.ac.uk%7Ceba3de1db9174976852b08dc6f7001a0%7C513def5bdf174107b5523dba009e5990%7C0%7C0%7C638507774058203135%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&amp;sdata=c8Nc%2B%2BqUFnfIoFkLqM7S6FS6PbXk8kKvIE8QvvOb2Zw%3D&amp;reserved=0">https://www.nature.com/articles/s41591-024-02960-5</a></span></p> <p>The columns are as follows:</p> <ul> <li>SNP: rs identifier for the SNP</li> <li>CHR: chromosome (GRCh37 build)&nbsp;</li> <li>BP: base pair (GRCh37 build)&nbsp;</li> <li>A1: effect allele&nbsp;</li> <li>A2: reference allele&nbsp;</li> <li>FREQ: effect allele frequency&nbsp;</li> <li>INFO: imputation information</li> <li>P: p-value&nbsp;</li> <li>BETA: effect size of effect allele</li> <li>SE: standard error&nbsp;</li> <li>N: sample size</li> </ul>