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RNAseq of partially paralyzed zebrafish embryos at 5 days post-fertilization compared to normal siblings

<p>Sofa potato (sop) is a mutant zebrafish line, whose synaptic transmission at the neuromuscular junction is absent due to a point mutation in the δ subunit gene of the acetylcholine receptor (AChR), leading to paralysis of its skeletal muscles. To explore genetic changes in embryos caused by the lack of synaptic transmission, we performed RNA-seq analysis of normal siblings (<em>sop</em><sup>+/?</sup>) and <em>sop </em>homozygous embryos<em> (sop<sup>-/-</sup>) </em>at 5 days post-fertilization.</p>

ShareScore

32/100

Overall dataset sharing score

Score breakdown

These five areas show where the dataset supports — or may limit — practical reuse.

Stewardship
4
Harmonization
8
Access
12
Reuse readiness
0
Engagement
8

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