Annotation data needed for FLAMES

<p>Annotation data needed for running FLAMES.</p> <p>All files ending in&nbsp;<strong>.tar.gz&nbsp;&nbsp;<em>must be unpacked before using.&nbsp;<br></em></strong>e.g. using tar -xzvf Annotation_data.tar.gz -C /path/to/extract, where /path/to/extract is the location where you want the files extracted.</p> <p>This page contains the following files:</p> <p><strong>Annotation_data.tar.gz</strong>&nbsp; - This gzipped file contains the data needed for the functional annotation of FLAMES. <br>Please extract the data before running FLAMES,</p> <p><strong>gtex_v8_ts_avg_log2TPM.txt</strong>&nbsp; - This file can be used for generating the tissue-type specific MAGMA results. <br>For a more detailed explanation see github.com/Marijn-Schipper/FLAMES</p> <p><strong>pops_features_full.tar.gz&nbsp;</strong>- This contains the data to recreate PoPS scores as used in the manuscript.</p> <p><strong>pops_features_pathway_naive.tar.gz </strong>- This contains the data to recreate pathway naive PoPS scores as used in the manuscript.</p> <p><strong>pops_features_pathway_FUMA_compatible.gz </strong>- This contains the data to recreate PoPS scores from MAGMA-Z files from ENSEMBL version 1.03-1.10, or FUMA MAGMA results.</p> <p><strong>pops_features_pathway_naive_FUMA_compatible.tar.gz </strong>- This contains the data to recreate pathway naive PoPS scores as used in the manuscript ENSEMBL version 1.03-1.10, or FUMA MAGMA results.<br>NOTE: This will allow for running PoPS on FUMA-generated MAGMA results, but will result in a PoPS score of 0 for genes not included in the original PoPS study.&nbsp;</p>