zenodoopen
Co-crystal structures of USP5 Zf-UBD and weak binding compounds
<p>Determination of crystallization conditions which allow growth of well-diffracting co-crystals of USP5 zinc finger ubiquitin binding domain (Zf-UBD) and compounds shown to bind weakly by <a href="https://zenodo.org/record/1283325#.Wz5VXtJKjIV">19F NMR</a> and <a href="https://zenodo.org/record/1311686#.W0il_tJKjIU">SPR assays</a> & to solve the co-crystal structures to determine if electron density of ligands can be seen in the binding pocket of the protein domain.</p>
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