Microscopy images - "An elevated rate of whole-genome duplications associated with carcinogen exposure in Black cancer patients"

<p>This repository contains microscopy data from the manuscript "An elevated rate of whole-genome duplications associated with carcinogen exposure in Black cancer patients" by Leanne M. Brown, Ryan A. Hagenson, Tilen Koklič, Iztok Urbančič, Janez Strancar, and Jason M. Sheltzer (preprint: 10.1101/2023.11.10.23298349; accepted for publication in Nature Communications).</p> <p>&nbsp;</p> <p>Each zip contains the set of images from individual multi-channel multi-position time-lapse experiment with different combinations of cells exposed to one nanomaterial. Files are named as: IMGxxxx_[ExperimentCode]_ROIxx_tile[TileNumber]_[Channel]_[CellType]_t[Timepoint].tif, where each of the varying elements in [..] denotes the following:</p> <ul> <li>[ExperimentCode]: tells which material the cells were exposed to - see decoding table in the file "material-codes.xlsx"</li> <li>[TileNumber]: two xy-tiles per condition</li> <li>[Channel]: cytoplasm of epi cells (LA4), membrane (MEM), cytoplasm of imu cells and tubulin (MHSTUB), nanomaterial (NANO)</li> <li>[CellType]: mono-culture of lung epithelial cells (epi), their coculture with macrophages (epiimu)</li> <li>[Timepoint]: consecutive number of the frame in the time-lapse</li> </ul> <p>&nbsp;</p>