Figure 3 in mir-331 negatively regulates thyroglobulin secretion via ERp29

Figure 3. Regulation of Tg expression and secretion by small interfering RNAs. (A) Regulation of ERp29 and ThrB expression using siERp29 and miRNA-331, respectively. (B) Regulation of Tg gene expression by siERp29 and miRNA-331. (C) Regulation of Tg secretion by siERp29 and miRNA-331. All experimental conditions in Figure 1 are described in the text. Data represent means ± standard deviation (SD) of at least 3 independent experiments. Statistical significance between multiple groups: one-way analysis of variance (ANOVA) test. GraphPad Prism 6 software (GraphPad Software Inc., San Diego, CA, USA). *P <0.05, **P <0.005, ***P <0.001, ****P <0.0001.