Fig. 2. T in Nasal vaccination of six squirrel monkeys (Saimiri sciureus): Improved immunization protocol against Toxoplasma gondii with a nanoparticle-born vaccine

Fig. 2. T-cell immune response analyzed by IFN-γ ELISPOT on PBMC from 6 Saimiris. The results are presented as Spot Forming Units for 106 PBMC (left), before the immunization (T0), one month after the prime, 5 months after the 1st boost and 2 months after the 2nd boost. A representative picture of the ELISPOT plate after the 2nd boost is presented (right). Only 4 animals were analyzed by ELISPOT after the 2nd boost due to blood coagulation in the sampling tubes. Statistical analyses were made by KruskalWallis test, * p <0.05, ** p <0.01.