Skip to main content
zenodoopen

Spatiotemporal dysregulation of neuron-glia related genes and pro-/anti-inflammatory miRNAs in the 5xFAD mouse model of Alzheimer's disease - Supplementary data

<p><strong>Supplementary Table 1.&nbsp;</strong> Gene expression profile &nbsp;by RT-qPCR analysis revealed no significant differences when simultaneously considering the genotype (WT/5xFAD), age (6/9 months) and brain region (HPC, hippocampus/PFC, prefrontal cortex).&nbsp;</p> <p><strong>Supplementary Table 2.</strong>&nbsp; miRNA-target table for the Analyzed microRNAs and targets selected for this study. Obtained in the online platform https://www.mirnet.ca/</p> <p><strong>Supplementary Table 3.&nbsp;</strong> Node table for the analyzed microRNAs and targets selected for this study. We only considered miRNAs and/or targets with a node degree of at least 2. Obtained in the online platform https://www.mirnet.ca/</p> <p><strong>Supplementary Table 4.</strong>&nbsp; Bivariate Pearson&rsquo;s correlation coefficients and respective p-values obtained between all miRNAs and genes.</p> <p><strong>Supplementary Table 5.</strong>&nbsp; &nbsp;List of microRNAs analyzed by RT-qPCR and their primer sequences.</p> <p><strong>Supplementary Table 6.</strong>&nbsp; List of genes and respective primer sequences used for mRNA analysis by RT-qPCR.</p> <p><strong>Supplementary Table 7.</strong>&nbsp; Raw data used for correlational analysis in hippocampus (HPC) and prefrontal cortex (PFC) using the cor function in RStudio software.</p>

ShareScore

40/100

Overall dataset sharing score

Score breakdown

These five areas show where the dataset supports — or may limit — practical reuse.

Stewardship
8
Harmonization
4
Access
16
Reuse readiness
8
Engagement
4

ScienceDex for faculty

Your academic CV and NIH biosketch

Make your CV in your school's format and your NIH biosketch from it, then download both as Word files.