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Storage conditions affect the composition of the lyophilized secretome of multipotent mesenchymal stromal cells - graphs

<p>Figures for artcile Rogulska, O., Vackova, I., Prazak, S.&nbsp;<em>et al.</em>&nbsp;Storage conditions affect the composition of the lyophilized secretome of multipotent mesenchymal stromal cells.&nbsp;<em>Sci Rep</em>&nbsp;14, 10243 (2024). https://doi.org/10.1038/s41598-024-60787-z</p> <p><span>Fig. 1. Preservation of the growth factors and cytokines in the lyophilized MSC-derived conditioned medium after 3 months of storage at different temperatures (N=3). Data is presented as Median (Q1; Q3). * - the values are significantly (p&lt;0.05) lower compared to the -80&deg;C group; # - the values are significantly (p&lt;0.05) lower compared to the -20&deg;C group. The values are related to non-lyophilized MSC-sec stored for the same time (3 months) in a frozen state at &minus;80&deg;C.</span></p> <p><span>&nbsp;</span><span>Fig. 2. The preservation of growth factors and cytokines in the lyophilized MSC-derived conditioned medium after 30 months of storage at different temperatures (N=3). Data is presented as Median (Q1; Q3). * - the values are significantly (p&lt;0.05) lower compared to the -80&deg;C group; # - the values are significantly (p&lt;0.05) lower compared to the -20&deg;C group; &deg; - the values are significantly (p&lt;0.05) lower compared to the 4&deg;C group. The values are related to non-lyophilized MSC-sec stored for the same time (30 months) in a frozen state at &minus;80&deg;C.</span></p> <p><span>&nbsp;</span><span>Fig. 3. The preservation levels of the whole lyophilized MSC-sec cocktail, determined as the median of the preservation values for each of the MSC-sec components. The v</span><span>alues are related to non-lyophilized MSC-sec stored for the same time in a frozen state at &minus;80&deg;C.</span></p>

ShareScore

44/100

Overall dataset sharing score

Score breakdown

These five areas show where the dataset supports — or may limit — practical reuse.

Stewardship
8
Harmonization
4
Access
20
Reuse readiness
8
Engagement
4

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