Targeting Plasmodium falciparum chondroitin sulfate a ligand: A highly conserved malaria antigen with potential for pregnancy-associated malaria vaccine development

<p>The dataset represents the details of sera samples collected from participants recruited for a longitudinal study. The sera was used for ELISA <em>in vitro</em> assays. The immunoreactivity of PfCSA-L antigen was assessed with the utilization of the gravidity status of the study participants. The antigen is used by the <em>plasmodium falciparum</em> parasite to adhere to the placenta during pregnancy and causes challenges both to the mother and her fetus.</p> <h5>Variables</h5> <ul> <li> <p>Sample_ID - This is the coded details of the study participant.</p> </li> <li> <p>Mean*od <em>_1st_visit, Mean</em>od <em>_2nd_visit, and Mean</em>od *_3rd_visit - These represent the mean reactivity values for antibody (IgG) to PfCSA-L antigen for antenatal visits 1,2 and 3 respectively.</p> </li> <li> <p>Gravida - Refers to the total number of confirmed pregnancies a female has had, regardless of the outcome of the pregnancy.</p> </li> <li> <p>PCR_Results - these are molecular diagnostic results for <em>Plasmodium falciparum</em> to assess whether the study participants were positive or negative for this species. positive = 1 and negative = 0</p> </li> <li> <p>Gestation..weeks - Refers to how far along the pregnancy is, from the first day of the woman's last menstrual cycle to the delivery</p> </li> <li> <p>Newborn outcome - Describes the health status of the childlren when they were born</p> </li> <li> <p>Gravida_class - Describes the different classes of gravida, such that primigravida means single pregnancy, secundigravida-second pregnancy, and tertigravida-third pregnancy</p> </li> <li> <p>Age - Describes the age of the participants recruited for the study</p> </li> <li> <p>HB_level - Describes the amount of hemoglobin in whole blood expressed in grams per deciliter (g/dl) during<br>enrolment</p> </li> <li> <p>Type of delivery - A spontaneous vaginal delivery (SVD) describes when a pregnant female goes into labor without the use of drugs or techniques to induce labor, and delivers her baby in the normal manner, without forceps, vacuum extraction, or a cesarean section (cs)</p> </li> <li> <p>N/A - Missing values for different variables</p> </li> </ul>