Single-molecule analysis of transcription activation: dynamics of SAGA co-activator recruitment

<p>Source data for:</p> <p><strong>Single-molecule analysis of transcription activation: dynamics of SAGA co-activator recruitment</strong></p> <p><strong>&nbsp;</strong></p> <p>Jongcheol Jeon¹, Larry J. Friedman², Daniel H. Zhou², Hogyu David Seo¹, Oluwatobi A. Adeleke³, Bria Graham³, Emily F. Patteson³, Jeff Gelles²*, and Stephen Buratowski^1,*</p> <p>&nbsp;</p> <p>¹Department of Biological Chemistry and Molecular Pharmacology,</p> <p>Harvard Medical School, Boston, MA 02115</p> <p>² Department of Biochemistry, Brandeis University, Waltham, MA 02454</p> <p>³ EpiCypher Inc., Durham NC 27709</p> <p>&nbsp;</p> <p>*Corresponding authors</p> <p>Lead author contact information:</p> <p><a href="mailto:steveb@hms.harvard.edu">steveb@hms.harvard.edu</a></p> <p>&nbsp;</p> <p>&nbsp;</p> <p>The source data for the single molecule experiments are provided as "intervals" files and "CoSMoS parameters", which can be read and manipulated using the publicly available programs "Imscroll" and "Tapqir", respectively:</p> <p><a href="https://github.com/gelles-brandeis/CoSMoS_Analysis">https://github.com/gelles-brandeis/CoSMoS_Analysis</a></p> <p><a href="https://github.com/gelles-brandeis/tapqir">https://github.com/gelles-brandeis/tapqir</a></p>