Gradual Pressure Error in an HPLC-HRMS Measurement Run

<p>This dataset contains files of a reverse-phase HPLC-HRMS orbitrap measurement run during which the pump pressure gradually got more unstable. While a run was being recorded, the pump for the organic eluent ceased functioning slowly. This resulted in a high amount of new signals appearing in the form of "stripes" at specific retention times.</p> <p>It is intended as a control group for assigned data quality scores, with the reasoning that a highly unstable pressure in the chromatography will lead to more purely noise-induced signals. The relevant pressure profiles are also included. The mzML files were produced from the raw data using MSconvert and only contain the MS1 spectra.</p> <p>The last file in the series (<a href="https://zenodo.org/api/records/14046512/draft/files/20240805_AA_DK_Ibu_pH6_1min_20240808161549.raw/content" target="_blank" rel="noopener noreferrer">20240805_AA_DK_Ibu_pH6_1min_20240808161549</a>) remains incomplete since the instrument shut off halfway through the measurement.</p>