Insights into Heterocycle Biosynthesis in the Cytotoxic Polyketide Alkaloid Janustatin A from a Plant-Associated Bacterium

<p>Data underlying the manuscript 'Insights into Heterocycle Biosynthesis in the Cytotoxic Polyketide Alkaloid Janustatin A from a Plant-Associated Bacterium' by Leopold-Messer, Chawengrum and Piel.</p> <p>The repository contains:</p> <p>Sequencing data - Genbanks files of construct designs and ab1 files from Sanger sequencing. Contains both plasmids used to construct mutants, as well as sequencing data from final mutants.</p> <p>NMR data - MestReNova files of compounds 2-4.</p> <p>HPLC-MS data - Raw data collected on Thermo-Fisher instruments for the purified compounds (1-4) and the extract of all mutants.&nbsp;</p> <p>EICs - extracted ion chromatograms used to analyse the metabolic differences between mutants. These data are based on the raw files.</p> <p>Bioactivity data - cytotoxicity data of compounds 1-4.&nbsp;</p>