Genome-wide association study identifies 18 novel loci associated with left atrial volume and function

<p><strong>README</strong></p> <p>Publication:&nbsp;Genome-wide association study identifies 18 novel loci associated with left atrial volume and function</p> <p>Ahlberg and Andreasen et al.</p> <p>Published: 29 July 2021,&nbsp;doi:&nbsp;<a href="https://doi.org/10.1093/eurheartj/ehab466">https://doi.org/10.1093/eurheartj/ehab466</a></p> <p>summary statistics&nbsp;for LAmax:&nbsp;rntrn_ilamax.bgen.stats.betastd.tsv.gz&nbsp;<br> summary statistics&nbsp;for LAmin:&nbsp;rntrn_ilamin.bgen.stats.betastd.tsv.gz&nbsp;<br> summary statistics&nbsp;for LAAEF: rntrn_laaef.bgen.stats.betastd.tsv.gz&nbsp;<br> summary statistics&nbsp;for LAPEF:&nbsp;rntrn_lapef.bgen.stats.betastd.tsv.gz&nbsp;<br> summary statistics&nbsp;for LATEF:&nbsp;rntrn_latef.bgen.stats.betastd.tsv.gz&nbsp;</p> <p>&nbsp;</p> <p>Description:</p> <p>SNP: rs number or ID string<br> CHR: chromosome<br> BP: physical (base pair) position<br> GENPOS: genetic position either from&nbsp;bim&nbsp;file or interpolated from genetic map<br> ALLELE1: first allele in&nbsp;bim&nbsp;file (usually the minor allele), used as the effect allele<br> ALLELE0: second allele in&nbsp;bim&nbsp;file, used as the reference allele<br> A1FREQ: frequency of first allele<br> F_MISS: fraction of individuals with missing genotype at this SNP<br> BETA: effect size from BOLT-LMM approximation to infinitesimal mixed model<br> SE: standard error of effect size<br> P_BOLT_LMM_INF: infinitesimal mixed model association test&nbsp;p-value<br> P_BOLT_LMM: non-infinitesimal mixed model association test&nbsp;p-value<br> N: sample size&nbsp;<br> bstd: standardized effect size from BOLT-LMM&nbsp;<br> sestd: standardized&nbsp;standard error of effect size</p>