Accompanying data set for the manuscript "REverSe TRanscrIptase Chain Termination (RESTRICT) for Selective Measurement of Nucleotide Analogs Used in HIV Care and Prevention"
<p>This data set contains all experimental and theoretical data included in the manuscript " REverSe TRanscrIptase Chain Termination (RESTRICT) for Selective Measurement of Nucleotide Analogs Used in HIV Care and Prevention", namely:</p> <p>RESTRICT_model: MATLAB script for completing calculations in the RESTRICT theoretical model.</p> <p>Figure 2:</p> <ul> <li>Raw data from theoretical model showing contributions of individual model components, Kaff = 0.3</li> <li>Normalized data from theoretical model showing contributions of individual model components, Kaff = 0.3</li> <li>Experimental NRTI Drug Screen 180 nt TTCA 500 nM dNTP</li> </ul> <p>Figure 3:</p> <ul> <li>Experiment-dNTP-Concentration-Screen</li> <li>Theory-dNTP-Concentration-Screen</li> <li>Experiment-Template-Length-Screen</li> <li>Theory-Template-Length-Screen</li> <li>Experiment-Sequence-Screen</li> <li>Theory-Sequence-Screen</li> </ul> <p>Figure 4:</p> <ul> <li>Experimental-NRTI-Drug-Screen-90nt-TCAA-only</li> <li>Theory-TCAA90-Kaff=0point2</li> <li>Experimental-NRTI-Drug-Screen-GGCA-only</li> <li>Theory-GGCA180-Kaff=0point2</li> </ul> <p>Figure 5:</p> <ul> <li>GGCA-vs-TTCA-Specificity-Analysis</li> </ul>
ShareScore
36/100
Overall dataset sharing score
Score breakdown
These five areas show where the dataset supports — or may limit — practical reuse.
- Stewardship
- 4
- Harmonization
- 4
- Access
- 16
- Reuse readiness
- 8
- Engagement
- 4