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Risk factors for treatment failure in women with uncomplicated lower urinary tract infection

<p><strong>Origin :</strong></p> <p>This dataset represent a sub-population of a previous clinical trial.&nbsp;</p> <blockquote> <p><a href="https://pubmed.ncbi.nlm.nih.gov/29710295/">Huttner A, Kowalczyk A, Harbarth S, et al.. Effect of 5-Day Nitrofurantoin vs Single-Dose Fosfomycin on Clinical Resolution of Uncomplicated Lower Urinary Tract Infection in Women: A Randomized Clinical Trial. JAMA. 2018;319(17):1781-1789. DOI: 10.1001/jama.2018.3627.</a></p> </blockquote> <p>&nbsp;</p> <p><strong>Databases :&nbsp;</strong></p> <ul> <li>1st database : women included in the nested cohort study (n=350)</li> <li>2nd database : women with microbiologically conformed UTI (n=279)</li> <li>3d database : women with&nbsp;<em>E.coli</em>&nbsp;related UTI&nbsp;(n=185)</li> </ul> <p><strong>Important :&nbsp;</strong></p> <ul> <li>Data from Tel Aviv have been removed from this&nbsp;dataset,&nbsp;and might be shared by the corresponding author&nbsp;upon reasonable request at the following address (romainmartischang@gmail.com).</li> </ul> <p><strong>Codebook :&nbsp;</strong></p> <ul> <li>v1_XXX; 0/1&nbsp;:&nbsp;All symptoms present at baseline</li> <li>v1dipstick : Negative (0), nitrites (1), leukocytes esterase (2), both (3), not done (4)</li> <li>centre : recruitment centre (CHE or POL)</li> <li>rfscore : risk factor for carrying a resistant bacteria as defined in the initial trial</li> <li>treatment&nbsp;: nitrofurantoin (0) vs fosfomycin (1)</li> <li>dm : diabetes mellitus&nbsp;</li> <li>case2&nbsp;: bacteriological failure at 28 days as defined in the initial trial</li> <li>case1&nbsp;: clinical failure at 28 days as defined in the initial trial</li> <li>recur14 :&nbsp;bacteriological failure at 14 days as defined in the initial trial</li> <li>fail14 :&nbsp;clinical failure at 14 days as defined in the initial trial</li> <li>v1pathogen[1-3] : pathogen present at baseline</li> </ul>

ShareScore

40/100

Overall dataset sharing score

Score breakdown

These five areas show where the dataset supports — or may limit — practical reuse.

Stewardship
8
Harmonization
4
Access
16
Reuse readiness
8
Engagement
4

Topics

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