A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma

<p>This repository contains R Seurat objects associated with our study titled "<strong>A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma</strong>".&nbsp;</p> <p>This repository contains two Seurat objects stored in .rds files containing processed single-cell RNA sequencing data from the original &lsquo;Discovery&rsquo; cohort of the MMRF Immune Atlas study, along with an additional &lsquo;Discovery + Validation&rsquo; cohort, as described in the original publication. These .rds files contain Seurat v4 objects with basic cell type annotation and qc metadata. Specific file contents will be detailed below.</p> <div> <p>A copy of the &lsquo;Cell Annotation Dictionary&rsquo; is also included, which contains additional details on the individual annotated clusters in the Immune Atlas dataset.</p> <p>Information on how to request additional metadata about these samples and accessing the original fastq files will be detailed at the end of this description</p> </div>