Efficient Real-Time Selective Genome Sequencing on Resource-Constrained Devices

<p>This dataset contains the curated nanopore&nbsp;raw signal data in <a href="https://www.nature.com/articles/s41587-021-01147-4">BLOW5 format </a>used to benchmark <a href="https://github.com/beebdev/HARU/">Hardware Accelerated Read Until (HARU)</a>. This dataset was created by using the publicly available datasets:&nbsp;<a href="https://community.artic.network/t/links-to-raw-fast5-fastq-data-for-artic-protocol/17">SARS-CoV-2 SP1</a>&nbsp;(1.382M reads)&nbsp;and <a href="https://ncbi.nlm.nih.gov/sra/SRX11368475">NA12878 PromethION subset</a>&nbsp;(500,000 reads). The tarball when extracted will have the following directory structure:</p> <p>haru-data<br> ├── na12878-rfc1<br> │&nbsp;&nbsp;&nbsp;├── blow5-rawsignal<br> │&nbsp;&nbsp;&nbsp;│&nbsp;&nbsp;&nbsp;├── na12878_dna_0.blow5<br> │&nbsp;&nbsp;&nbsp;│&nbsp;&nbsp;&nbsp;├── na12878_dna_100.blow5<br> │&nbsp;&nbsp;&nbsp;│&nbsp;&nbsp;&nbsp;├── na12878_dna_101.blow5<br> │&nbsp;&nbsp;&nbsp;│&nbsp;&nbsp;&nbsp;├── na12878_dna_102.blow5<br> │&nbsp;&nbsp;&nbsp;│&nbsp;&nbsp;&nbsp;├── ...<br> │&nbsp;&nbsp;&nbsp;└── reference<br> │&nbsp;&nbsp;&nbsp; &nbsp; &nbsp;└── rfc1.fa<br> └── SARS-CoV-2-sp1<br> &nbsp; &nbsp; ├── blow5-rawsignal<br> &nbsp; &nbsp; │&nbsp;&nbsp;&nbsp;├── readgroup0<br> &nbsp; &nbsp; │&nbsp;&nbsp;&nbsp;│&nbsp;&nbsp;&nbsp;├── reads_0_0.blow5<br> &nbsp; &nbsp; │&nbsp;&nbsp;&nbsp;│&nbsp;&nbsp;&nbsp;├── reads_0_10.blow5<br> &nbsp; &nbsp; │&nbsp;&nbsp;&nbsp;│&nbsp;&nbsp;&nbsp;├── reads_0_11.blow5<br> &nbsp; &nbsp; │&nbsp;&nbsp;&nbsp;│&nbsp;&nbsp;&nbsp;├── reads_0_12.blow5<br> &nbsp; &nbsp; │&nbsp;&nbsp;&nbsp;│&nbsp;&nbsp;&nbsp;├── ...<br> &nbsp; &nbsp; │&nbsp;&nbsp;&nbsp;└── readgroup1<br> &nbsp; &nbsp; │&nbsp;&nbsp;&nbsp; &nbsp; &nbsp;├── reads_1_0.blow5<br> &nbsp; &nbsp; │&nbsp;&nbsp;&nbsp; &nbsp; &nbsp;├── reads_1_10.blow5<br> &nbsp; &nbsp; │&nbsp;&nbsp;&nbsp; &nbsp; &nbsp;├── reads_1_11.blow5<br> &nbsp; &nbsp; │&nbsp;&nbsp;&nbsp; &nbsp; &nbsp;├── ....<br> &nbsp; &nbsp; └── reference<br> &nbsp; &nbsp; &nbsp; &nbsp; └── nCoV-2019.reference.fasta</p> <p>nCoV-2019.reference.fasta is the SARS-CoV-2&nbsp;MN908947.3 reference genome. rfc1.fa is the genomic region&nbsp;hr4:39262456-39391375 extracted from hg38 human genome.&nbsp;</p> <p>&nbsp;</p> <p>&nbsp;</p>