Activation patterns of afferent synapses on layer 5 tufted pyramidal cells in a biologically detailed simulation

<p>The data set is based on a biologically detailed simulation of a circuit of cortical neurons. The circuit was activated by thalamo-cortical inputs every 1 s for 500 ms. We report for a number of exemplary tufted pyramidal cells in layer 5 the pattern activation of their afferent synapses.</p> <p>Specifically, we report for all afferent excitatory synapses the pairwise path distances along the dendrite / soma (note that the soma was simplified to a point for the purpose of calculating path distances, but not during the simulation), and the times of activation of each of these synapses.</p> <p>The simulation is based on the model described in <a href="https://www.biorxiv.org/content/10.1101/2022.08.11.503144v1">this preprint</a>. The model can also be found <a href="https://zenodo.org/record/6906785">here on Zenodo</a>. For more details on the simulation, contact the author.</p> <p>For more details about the format of the data, refer to the included jupyter notebook.</p>