Dataset related to: "Effectiveness of pulmonary rehabilitation in individuals with Chronic Obstructive Pulmonary Disease according to inhaled therapy: The Maugeri study"

<p>We provide the raw data used for the following article:</p> <p>Vitacca M, Paneroni M, Spanevello A, Ceriana P, Balbi B, Salvi B, Ambrosino N. <strong>Effectiveness of pulmonary rehabilitation in individuals with Chronic Obstructive Pulmonary Disease according to inhaled therapy: The Maugeri study.</strong> Respir Med. 2022 Oct;202:106967. doi: 10.1016/j.rmed.2022.106967.&nbsp;</p> <p>ABSTRACT</p> <p>Background and aim: Real-life studies report discordant prescribing of inhaled triple therapy (TT) among individuals<br> with COPD. Guidelines recommend pulmonary rehabilitation (PR) for persistent breathlessness and/or<br> exercise limitation. This real-life study aimed to assess the effects of in-patient PR in individuals under TT as<br> compared to other inhaled therapies (no TT).<br> Methods: Multicentric, retrospective analysis of data from individuals admitted to in-hospital PR. Baseline<br> characteristics were recorded and lung function was assessed. Outcome measures were: 6-min walking test<br> (6MWT: primary outcome), Medical Research Council (MRC) scale for dyspnoea, and COPD assessment test<br> (CAT).<br> Results: Data of pre and post program 6MWT of 1139 individuals were available. Pulmonary rehabilitation<br> resulted in significant improvement in 6MWT in both groups, however, the effect size (by 54.3 &plusmn; 69.7 vs 42.5 &plusmn;<br> 64.2 m, p = 0.004) and proportion of individuals reaching the minimal clinically important difference (MCID) of<br> 6MWT (64.2%, vs 54.3%, p = 0.001) were higher in TT group. Both groups significantly improved also the other<br> outcome measures. The significant independent predictors of reaching the MCID of 6MWT were hospital provenience,<br> TT use, and high eosinophils count.<br> Conclusion: Pulmonary rehabilitation results in significant benefits in individuals with COPD irrespective of the<br> use of TT. However, individuals under TT report larger benefits in exercise tolerance than those under no TT.</p>