Noncanonical electromechanical coupling paths in cardiac hERG potassium channel (semi-binary contact maps)

<p>Matrices of the semi-binary contact maps of the following open and closed systems: WT, A527L, A614G, L524R, L529H, L532H, T425L, T618L, W563L.</p> <p>The residue numbering&nbsp;is not the official one because the first residues (397) of hERG (PAS domain) were not included in our simulations so that each subunit comprizes 466 residues. Moreover, the four subunits were numbered consecutively. The official numbering of a residue can be easily recovered. The general rule is:</p> <p>official residue - 397 = our residue</p> <p>For example, the official T425 corresponds to T28 in the first subunit (425-397), T494 in the second subunit (425-397+466), T960 in the third subunit (425-397+466+466), and T1426 in the fourth subunit (425-397+466+466+466).</p>