Skip to main content
zenodorestricted

Supplementary processed data for Chandler et al. Single-cell transcriptomics identifies aberrant glomerular angiogenic signalling in the early stages of a murine model of WT1 kidney disease

<p><strong><em>Summary datafiles for Chandler et al.</em></strong></p> <ul> <li>Processed single-cell RNA sequencing data, derived from murine glomeruli (isolated using the dynabead technique) from <em>n = 2</em> wild-type <em>Wt1<sup>+/+</sup></em> (Ctrl) and <em>n = 2</em> mutant <em>Wt1<sup>R394W/+</sup></em> (Mut) littermates of WT1 glomerulopathy, followed by 10x Genomics Chromium v3 platform.</li> <li>Please refer to associated scripts for analysis of the data:&nbsp;<a href="https://github.com/daniyal-jafree1995/collaborations/blob/main/Chandleretal_2022_WT1glomerulopathyscRNAseq.R">https://github.com/daniyal-jafree1995/collaborations/blob/main/Chandleretal_2022_WT1glomerulopathyscRNAseq.R</a>&nbsp;</li> <li>File descriptions as below: <ul> <li>barcodes.tsv.gz - barcodes file required for input to Read10X function in Seurat</li> <li>features.tsv.gz - features&nbsp;file required for input to Read10X function in Seurat</li> <li>matrix.mtx.gz -&nbsp;matrix&nbsp;file required for input to Read10X function in Seurat</li> <li>WT1_scRNAseq.rds - RDS file containing processed and annotated Seurat object for downstream analysis</li> </ul> </li> </ul>

ShareScore

12/100

Overall dataset sharing score

Score breakdown

These five areas show where the dataset supports — or may limit — practical reuse.

Stewardship
8
Harmonization
4
Access
0
Reuse readiness
0
Engagement
0

Topics

Dataset details

Repository
zenodo
Published
January 23, 2023
License
Not reported
DOI
10.5281/zenodo.7565866

Scored with release 0.9.0

ScienceDex for faculty

Your academic CV and NIH biosketch

Make your CV in your school's format and your NIH biosketch from it, then download both as Word files.