Genome-wide analyses of DNA Copy Number and somatic mutations of high hyperdiploid acute lymphoblastic leukemia

<p>This is a data record for&nbsp;copy number analysis and somatic single nucleotide variants analysis of high hyperdiploid acute lymphoblastic leukemia (ALL) in the manuscript: Clonal origin and development of high hyperdiploidy in childhood acute lymphoblastic leukemia.</p> <p>mutations.zip&nbsp;included 22 samples with high hyperdiploid ALL collected from the Division of Clinical Genetics, Lund University, Sweden. All samples were subjected to whole genome sequencing and somatic variants were identified by the GDC DNA-Seq analysis pipeline (Zhang et al.,2021). The data was stored in variant call format (vcf) and the interpretation of the file is available at: https://docs.gdc.cancer.gov/Data/File_Formats/VCF_Format/.</p> <p>TAPS.zip included 577 samples with high hyperdiploid ALL that were collected from four different cohorts. All samples were genotyped using either the Affymetrix SNP Array, Illumina&#39;s BeadArray platform or the whole genome/exome sequencing. Copy number alterations analysis was performed using TAPS and the graphics produced by TAPS are available for download. The interpretation of the figure is available at: https://patchwork.r-forge.r-project.org. This dataset has been used for copy number aberrations analysis for high hyperdiploid ALL.</p> <p>&nbsp;</p>