Data for patient-specific solution of the electrocorticography forward problem in deforming brain

<p>This dataset contains magnetic resonance (MR) and computed tomography (CT) images of a patient undergoing intracranial electrical monitoring using electrocorticography grid electrodes, together with patient-specific geometry and computational grids created from these images applied in the research reported in NeuroImage article &ldquo;Patient-specific solution of the electrocorticography forward problem in deforming brain&rdquo;. The images were acquired at Boston Children&rsquo;s Hospital and provided to The University of Western Australia&rsquo;s Intelligent Systems for Medicine Laboratory for analysis. The analysis was conducted using our open-source SlicerCBM software extension for the 3D Slicer medical imaging platform. The analysis steps include image processing to obtain the patient-specific brain geometry, construction of computational grids (tetrahedral grid for meshless solution of biomechanical model and regular hexahedral grid for finite element solution of the electrocorticography forward problem), biomechanics-based image warping to predict the postoperative images corresponding to the brain configuration deformed by placement of subdural electrodes, and patient-specific solution of the electrocorticography forward problem to compute the electric potential distribution within the patient&rsquo;s head. We use well-established open-source data file formats including Nearly Raw Raster Data (NRRD) files for images, STL files for surface geometry and Visualization Toolkit (VTK) files for computational grids. This facilitates the re-use of this dataset in a range of studies that rely on medical image analysis, and computational biomechanics and electrostatics to solve the electrocorticography forward problem for electrical source imaging.</p>