Human iPSC-derived microglia carrying LRRK2-G2019 mutation show Parkinson's disease related transcriptional profile and functions

<p>This repository contains the data and the code used in Ohtone Sohvi&#39;s project.</p> <p>A folder can contain the starting raw data in &quot;data&quot;, the R scripts in order of execution (op1, op2 ..) and the &quot;output&quot; folder that contains the final processed data of each operation.</p> <ul> <li>&quot;PD_bulk_analysis&quot; contains the processing and analysis of the bulk RNA sequencing data</li> <li>&quot;PD_bulk_fastq&quot; contains the raw fastq sequences of the bulk RNA sequencing</li> <li>&quot;PD_bulk_nfcore&quot; contains the results of processing the fasta sequences with nfcore rnaseq workflow&nbsp;</li> <li>&quot;PD_scRNA_analysis&quot; contains the analysis of the snRNA sequencing dataset</li> <li>&quot;PD_spatial&quot; contains the raw data of the spatial sequencing, the assempbly of the spatial expression profiles starting from the DAPI images and the transcripts coordinates, the analysis performed on the data</li> </ul>