Basaloid Squamous Cell Carcinoma: A Case Report

<p><strong>Background:</strong> The upper aerodigestive tract is where BSCC (basaloid squamous cell carcinoma), a rare variation of conventional SCC, is most frequently found. The hypopharynx, tonsil, supraglottic larynx, tongue (base), and head-neck regions are particularly susceptible to BSCC. Clinically, the presentation of BSCC is similar to that of conventional SCC, but it has a poor prognosis than traditional SCC. BSCC is distinguished histopathologically by a dimorphic-pattern, a distinctive basal cell component paired with a squamous component, and a squamous component. Compared to traditional SCC, the prognosis for BSCC is worse. However, clinically it shows similar features like conventional SCC which makes it difficult to diagnose. Therefore, histopathology and immunohistochemistry have a crucial role in diagnosing such tumors. We here present a case of a seventy-year male diagnosed with BSCC involving the tongue.</p> <p><strong>Keywords</strong>: Basaloid squamous cell carcinoma, dimorphic pattern, basaloid cells, comedo necrosis.</p>