Asp138 orientation correlates with ligand subsite occupancy.

<p>This directory contains all files required to plot Asp138 orientation against ligand subsite occupancy across all&nbsp;mouse AMCase&nbsp;structures presented in <strong>Figure 3</strong> of&nbsp;<a href="https://www.biorxiv.org/content/10.1101/2023.06.03.542675">D&iacute;az et al.<em> </em>(2023)</a>.</p> <p>Data was analyzed using Graphpad Prism. Figures were compiled using Adobe Illustrator.</p> <p>&nbsp;</p> <p><strong>Figures</strong></p> <p>- contains PDFs&nbsp;of the occupancy at sugar-binding subsite across all mouse AMCase models presented in D&iacute;az et al., (2023).</p> <p>&nbsp;</p> <p><strong>Occupancy.pzfx&nbsp;</strong></p> <p>- contains raw data and plots of ligand occupancy, and Asp138 <em>active</em>&nbsp;conformation occupancy.</p> <p>&nbsp;</p> <p>Contact:<br> Roberto Efra&iacute;n D&iacute;az, robertoefrain.diaz@ucsf.edu</p> <p>James Fraser, jfraser@fraserlab.com</p>