Fig. 21 in A comprehensive review: Biological activity, modification and synthetic methodologies of prenylated flavonoids

Fig. 21. Synthesis of prenylated flavonoids derivatives (551–563). Reagents and conditions: (a) Pd(OAc), AgAc, AcOH, dry toluene, N, 40 ◦ C, 8 h, 12–60%; (b) 2 2 SeO, 1,4-dixolane, 65 ◦ C, 2 h, 27%; (c) CH I, K CO, acetone, RT, 1 h, 87–94%; (d) butyldimethylsilyl-chloride, imidazole, dry CH Cl, RT, 12 h, 71%; (e) p- 2 3 2 3 2 2 bromobenzoyl/thiophene-2-carbonyl/acylchloride/tosyl/naphthalene-2-sulfonyl, dry pyridine, RT, 12 h, 73–82%; (f) 10% Pd/C, CH2Cl2, 10 h, 89%.