CRISPR-based engineering of RNA viruses

<p>CRISPR RNA-guided endonucleases have enabled precise editing of DNA. However, options for editing RNA remain limited. Here, we combine sequence-specific RNA cleavage by CRISPR ribonucleases with programmable RNA repair to make precise deletions and insertions in RNA. This work establishes a new recombinant RNA technology with immediate applications for the facile engineering of RNA viruses.</p> <p>&nbsp;</p> <p>This dataset contains code for analyzing sequencing data and generating figures in the manuscript.</p>