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Fig. 6. C3 activated the Nrf2 in Triterpenoids from Uncaria macrophylla as ferroptosis inhibitors

Fig. 6. C3 activated the Nrf2/SLC7A11/GPx4 axis. (A) C3 increased the protein levels of Nrf2, SLC7A11 and GPx4 in a dose-dependent manner. (B) ML385 treatment abolished the neuroprotective effect of C3 in PC12 cells. (C) ML385 blocked the activation of Nrf2, SLC7A11 and GPx4.

ShareScore

32/100

Overall dataset sharing score

Score breakdown

These five areas show where the dataset supports — or may limit — practical reuse.

Stewardship
8
Harmonization
4
Access
12
Reuse readiness
8
Engagement
0

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