Fig. 8. Compound 4 in Artemidubolides A T, cytotoxic unreported guaiane-type sesquiterpenoid dimers against three hepatoma cell lines from Artemisia dubia

Fig. 8. Compound 4 inhibited migration and invasion of HepG2 cells. HepG2 cells were treated with different concentrations (0.0, 3.5, 7.0 and 10.5 μM) of 4 for 48 h. (A) Representative photographs of the Transwell assay showed migrated and invaded cells after incubation. (B) Histogram of migrated and invaded cells after incubation. *P <0.05, **P <0.01, and ***P <0.001, n = 3.