Fig. 6 in Isoindolines and phthalides from the rhizomes of Ligusticum chuanxiong and their relaxant effects on the uterine smooth muscle

Fig. 6. Inhibitory effect of riligustilide (12) on KClinduced contraction of isolated rat uteruses. The final concentration of KCl was 60 mM. VER (0.5 μM) is the abbreviation for verapamil hydrochloride, a positive control. A: Traces for the effects of DMSO, VER, and riligustilide (12) on KCl-induced contraction in isolated rat uteruses. B: The inhibition rates of contractile tension of VER and riligustilide (12). The data are expressed as the mean ± SEM (n = 6). * indicates p <0.05 and ** indicates p <0.01 compared to the solvent control.