Fig. 6 in Polyacetylenes in herbal medicine: A comprehensive review of its occurrence, pharmacology, toxicology, and pharmacokinetics (2014-2021)

Fig. 6. Schematic representation of the possible mechanism of immunoregulation activity of polyacetylenes. (COX-2, cyclo-oxygenase-2; GATA-3, GATA binding protein 3; GM-CSF, granulocyte macrophage-colony stimulating factor; IFN-γ, interferon-γ; IL-1/4/5/6/10, interleukin-1/4/5/6/10; NF-κB, nuclear factor κB; STAT3/6, signal transducer and activator of transcription 3/6; TGF-β, transforming growth factor-β; TNF-α, tumor necrosis factor-α; Th1/2/17 lymphocyte, helper T type 1/2/17; Treg cell, regulatory T cell).