Fig. 5 in Site directed mutagenesis of Catharanthus roseus (+)-vincadifformine 19-hydroxylase (CYP71BY3) results in two distinct enzymatic functions

Fig. 5. The four residues in the V19H (left) and T3O (right) binding sites that were predicted to affect the opposite enantioselectivity of these highly homologous enzymes using models created on the 3ruk template. Residues shown in the V19H pocket are K106, S312, A376, and F377. Residues shown in the T3O pocket are R105, T311, P375, and L377. The model generated for T19H (3ruk template) looks identical to the T3O pocket, and the correlating residues are R101, T310, P374, and L375.