Fig. 2 in Site directed mutagenesis of Catharanthus roseus (+)-vincadifformine 19-hydroxylase (CYP71BY3) results in two distinct enzymatic functions

Fig. 2. Representation of the 3ruk V19H model superimposed onto the 3ruk template and the location of the catalytic heme. V19H model (purple) is shown in purple, and the 3ruk template is shown in pink with the heme binding site in yellow. The H-bond interaction (green) between PHE443 and CYS450, the first and eighth residues of the heme binding site, which is responsible for the beta bulge (yellow) around the heme cofactor (black). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)