Fig. 6. Overlapped top-scored poses for ligands 19 in Monoterpene indole alkaloids from Vinca minor L. (Apocynaceae): Identification of new structural scaffold for treatment of Alzheimer's disease

Fig. 6. Overlapped top-scored poses for ligands 19 (blue) and crystal structure of tacrine (green) in the active site of hBuChE (PDB ID: 4BDS). Amino acid residues involved in the interactions with ligands are depicted as either grey or yellow (catalytic triad) lines. The rest of the receptor is displayed in light-grey cartoon conformation. The Figure was created with The PyMOL Molecular Graphics System, Version 2.4.1, Schr¨odinger, LLC. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)