Fig. 8 in Five undescribed steroids from Talaromyces stipitatus and their cytotoxic activities against hepatoma cell lines

Fig. 8. Nuclear morphology changes in Hep3B cells assessed by fluorescence microscopy using DAPI staining. Cells were incubated for 48 h with (a) 0.2% DMSO; (b) compound 4 at 5 μM; (c) compound 8 at 5 μM; and (d) sorafenib at 3.5 μM. Arrows show apoptotic cells. The results are representative of three different experiments.