Fig. 54 in The scope of flavin-dependent reactions and processes in the model plant Arabidopsis thaliana

Fig. 54. Mechanism of Erv and Ero as partners for protein disulfide isomerase. In contrast to quiescin sulfhydryl oxidase, Erv and Ero do not interact directly with client proteins but serve to keep protein disulfide isomerase in an active oxidized state in order to allow for the proper generation of disulfide bonds in client proteins. Reduced Erv and Ero are reoxidized by dioxygen giving rise to the production of hydrogen peroxide.