Fig. 2. The aspartate 4 in Genomic insights into the biosynthesis and physiology of the cyanobacterial neurotoxin 2,4-diaminobutanoic acid (2,4-DAB)

Fig. 2. The aspartate 4-phosphate pathway. Established routes to 2,4-diaminobutanoate (2,4-diaminobutanoic acid) and derivatives. The nomenclature is from www.brenda-enzymes.org; the Enzyme Commission numbers are as follows: (1) aspartate transaminase: EC 2.6.1.1; (2) aspartate kinase: EC 2.7.2.4; (3) aspartate-semialdehyde dehydrogenase: EC 1.2.1.11; (4) diaminobutanoate- 2-oxo-glutarate transaminase: EC 2.6.1.76; (5) diaminobutanoate acetyltransferase: EC 2.3.1.178; (6) ectoine synthase: EC 4.2.1.108; and (7) ectoine hydroxylase: EC 1.14.11.55. Multiple-step pathways are indicated by *.