Fig. 3 in A pair of threonines mark ent-kaurene synthases for phytohormone biosynthesis

Fig. 3. Identification of the TT motif. A) Representative alignment of KSs spanning plant evolution with the KS specific pair of threonines (TT motif) indicated by asterisks (*) above the alignment. B) Sequence logos demonstrating the absolute conservation of this TT motif in KS (bottom) relative to the derived KS(L)/TPS-e subfamily more generally (top). C) Location of TT motif in active site from model of AtKS (blue) containing 2-fluoroGGPP (green) and Mg2+ co-factors (magenta) derived from the template co-crystal structure of taxadiene synthase (Koksal et al., 2011).