ProteinCartography v0.4 analyses for sample of most-studied human proteins

<p>Results from running the ProteinCartography pipeline (v0.4) using analyses on 25 proteins sampled from the most-studied human proteins listed in <a href="https://onlinelibrary.wiley.com/doi/10.1002/pro.4038">Liu and Buck, 2021</a>.<br> <br> The proteins included are listed in the table below. The results for each analysis are provided as individually-zipped folders, with the name of the file reflective of the protein name.&nbsp;To download all of the analyses in one folder, you can download the &quot;25humanprotein_analysis.zip&quot; file.</p> <table> <tbody> <tr> <td> <p><strong>UniProt ID</strong></p> </td> <td> <p><strong>Protein name</strong></p> </td> <td> <p><strong>Protein symbol (in figures)</strong></p> </td> </tr> <tr> <td> <p><strong>Q9UM73</strong></p> </td> <td> <p><strong>ALK tyrosine kinase receptor</strong></p> </td> <td> <p><strong>ALK</strong></p> </td> </tr> <tr> <td> <p><strong>Q96RI1</strong></p> </td> <td> <p><strong>Bile acid receptor</strong></p> </td> <td> <p><strong>NR1H4</strong></p> </td> </tr> <tr> <td> <p><strong>P43235</strong></p> </td> <td> <p><strong>Cathepsin K</strong></p> </td> <td> <p><strong>CATK</strong></p> </td> </tr> <tr> <td> <p><strong>P08603</strong></p> </td> <td> <p><strong>Complement factor H</strong></p> </td> <td> <p><strong>CFAH</strong></p> </td> </tr> <tr> <td> <p><strong>P00374</strong></p> </td> <td> <p><strong>Dihydrofolate reductase</strong></p> </td> <td> <p><strong>DYR</strong></p> </td> </tr> <tr> <td> <p><strong>P98170</strong></p> </td> <td> <p><strong>E3 ubiquitin-protein ligase XIAP</strong></p> </td> <td> <p><strong>XIAP</strong></p> </td> </tr> <tr> <td> <p><strong>P49841</strong></p> </td> <td> <p><strong>Glycogen synthase kinase-3 beta</strong></p> </td> <td> <p><strong>GSK3B</strong></p> </td> </tr> <tr> <td> <p><strong>P01112</strong></p> </td> <td> <p><strong>GTPase HRas</strong></p> </td> <td> <p><strong>RASH</strong></p> </td> </tr> <tr> <td> <p><strong>P68871</strong></p> </td> <td> <p><strong>Hemoglobin subunit beta</strong></p> </td> <td> <p><strong>HBB</strong></p> </td> </tr> <tr> <td> <p><strong>P04439</strong></p> </td> <td> <p><strong>HLA class I histocompatibility antigen, A alpha chain</strong></p> </td> <td> <p><strong>HLAA</strong></p> </td> </tr> <tr> <td> <p><strong>P01834</strong></p> </td> <td> <p><strong>Immunoglobulin kappa constant</strong></p> </td> <td> <p><strong>IGKC</strong></p> </td> </tr> <tr> <td> <p><strong>P14174</strong></p> </td> <td> <p><strong>Macrophage migration inhibitory factor</strong></p> </td> <td> <p><strong>MIF</strong></p> </td> </tr> <tr> <td> <p><strong>P53779</strong></p> </td> <td> <p><strong>Mitogen-activated protein kinase 10</strong></p> </td> <td> <p><strong>MK10</strong></p> </td> </tr> <tr> <td> <p><strong>Q15596</strong></p> </td> <td> <p><strong>Nuclear receptor coactivator 2</strong></p> </td> <td> <p><strong>NCOA2</strong></p> </td> </tr> <tr> <td> <p><strong>Q99497</strong></p> </td> <td> <p><strong>Parkinson disease protein 7</strong></p> </td> <td> <p><strong>PARK7</strong></p> </td> </tr> <tr> <td> <p><strong>P62937</strong></p> </td> <td> <p><strong>Peptidyl-prolyl cis-trans isomerase A</strong></p> </td> <td> <p><strong>PPIA</strong></p> </td> </tr> <tr> <td> <p><strong>Q13451</strong></p> </td> <td> <p><strong>Peptidyl-prolyl cis-trans isomerase FKBP5</strong></p> </td> <td> <p><strong>FKBP5</strong></p> </td> </tr> <tr> <td> <p><strong>P27986</strong></p> </td> <td> <p><strong>Phosphatidylinositol 3-kinase regulatory subunit alpha</strong></p> </td> <td> <p><strong>P85A</strong></p> </td> </tr> <tr> <td> <p><strong>O75530</strong></p> </td> <td> <p><strong>Polycomb protein EED</strong></p> </td> <td> <p><strong>EED</strong></p> </td> </tr> <tr> <td> <p><strong>P28074</strong></p> </td> <td> <p><strong>Proteasome subunit beta type-5</strong></p> </td> <td> <p><strong>PSB5</strong></p> </td> </tr> <tr> <td> <p><strong>P19793</strong></p> </td> <td> <p><strong>Retinoic acid receptor RXR-alpha</strong></p> </td> <td> <p><strong>RXRA</strong></p> </td> </tr> <tr> <td> <p><strong>P50120</strong></p> </td> <td> <p><strong>Retinol-binding protein 2</strong></p> </td> <td> <p><strong>RET2</strong></p> </td> </tr> <tr> <td> <p><strong>P00441</strong></p> </td> <td> <p><strong>Superoxide dismutase [Ccu-Zn]</strong></p> </td> <td> <p><strong>SODC</strong></p> </td> </tr> <tr> <td> <p><strong>Q93009</strong></p> </td> <td> <p><strong>Ubiquitin carboxyl-terminal hydrolase 7</strong></p> </td> <td> <p><strong>UPB7</strong></p> </td> </tr> <tr> <td> <p><strong>P40337</strong></p> </td> <td> <p><strong>von Hippel -&sbquo;&Auml;&igrave;Lindau disease tumor suppressor</strong></p> </td> <td> <p><strong>VHL</strong></p> </td> </tr> </tbody> </table> <p>A TSV file, &quot;most_studied_human_proteins.tsv&quot;, is included for use with the analysis notebook (&quot;pub/most_studied_human_proteins.ipynb&quot;) found in our <a href="https://github.com/Arcadia-Science/ProteinCartography">GitHub repository</a> for the Arcadia Science Pub &quot;<a href="https://doi.org/10.57844/arcadia-a5a6-1068">ProteinCartography: Comparing proteins with structure-based maps for interactive exploration</a>&quot;. The notebook produces the outputs, &quot;sampled_proteins.tsv&quot;, and. &quot;most_studied_human_proteins_analysis.tsv&quot;, which are used by the analysis notebook (&quot;pub/cluster_quality_human_proteins.ipynb&quot;), which uses the contents of this deposition.</p> <p>&nbsp;</p>