Cognitive function in DMD carriers: personal case series and literature review

<p>Introduction: This database includes the raw data linked with the paper &ldquo;Cognitive function in DMD carriers: personal case series and literature review&rdquo; published on &ldquo;Acta Myologica&rdquo;. Aim: This study aimed to investigate the cognitive involvement in a cohort of DMD carriers.</p> <p>Methods: Our case series consisted of 22 carrier patients from two different centers (IRCCS Mondino, Pa- via and Policlinico Gemelli, Rome), for whom we retrospectively collected cognitive, clinical and genetic data.</p> <p>Results: We found that the average IQ of DMD carriers was lower (74; very low) than the average score on normal curve (100 as average standard score). Furthermore, about 50% of them fell in the &ldquo;extremely low IQ&rdquo; range, compared with 2-3% of general population. A higher incidence of intellectual disability was confirmed&nbsp; in symptomatic DMD carriers (mean IQ 66; extremely low) from the IRCCS Mondino, but not for the asymptomatic ones (mean IQ 99; average), when compared to the general population.</p>