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Genetic variants (chr. 6) from Old World Schistosoma mansoni exomes

<p>Variant calling file (VCF) produced from exome libraries of <em>Schistosoma mansoni</em> (bloodfluke) samples from the Old Wold (West Africa (Senegal, Niger), East Africa (Tanzania), and Middle East (Oman)). One sample form the New World (Caribbean (HR9)) was added for comparison. The variants were called on the 3 Mb of chromosome 6 centered on the <em>SmSULT-OR</em> gene. This gene is involved in resistance to the drug oxamniquine&nbsp; (OXA). The aim of the related article was to investigate the origin of OXA resistant mutations in the New Wolrd by identifying sequence variation in <em>SmSULT-OR</em> in <em>S. mansoni</em> from the Old World, where OXA has seen minimal usage.</p>

ShareScore

44/100

Overall dataset sharing score

Score breakdown

These five areas show where the dataset supports — or may limit — practical reuse.

Stewardship
8
Harmonization
4
Access
20
Reuse readiness
8
Engagement
4

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