Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
231
datasets available to search
ShareScore release 0.9.0
Dataset results
231 results for “Avian Influenza”
Identification of avian RIG-I responsive genes during influenza infection
GEO Series GSE29596. Gallus gallus. 10 samples. Type: Expression profiling by array.
Gene expression analysis of chicken dendritic cells (DCs) in response to H9N2 avian influenza virus infection
GEO Series GSE117163. Gallus gallus. 6 samples. Type: Expression profiling by high throughput sequencing.
Expression data of lungs of mice infected with two highly pathogenic avian influenza viruses
GEO Series GSE41126. Mus musculus. 9 samples. Type: Expression profiling by array.
Inflammatory, transcriptomic and cell fate responses underlying the mammalian transmission of avian influenza viruses, bulk RNAseq.
GEO Series GSE296526. Mustela putorius furo. 20 samples. Type: Expression profiling by high throughput sequencing.
Gene Editing of Anp32a Confers Resistance to Avian Influenza in Chicken
GEO Series GSE182397. Gallus gallus. 32 samples. Type: Expression profiling by high throughput sequencing.
Host Regulatory Network Response to Infection with Highly Pathogenic H5N1 Avian Influenza Virus
GEO Series GSE28166. Homo sapiens. 36 samples. Type: Expression profiling by array.
Cytomegalovirus vaccine vector-induced effector memory CD4+ T cells protect cynomolgus macaques from lethal aerosolized heterologous avian influenza
GEO Series GSE268204. Macaca fascicularis. 84 samples. Type: Expression profiling by high throughput sequencing.
The 1918 PB2 protein, not HA, enhances the virulence of an avian influenza virus closely related to the 1918 pandemic virus through the inhibition of wnt signaling.
GEO Series GSE70502. Mus musculus. 66 samples. Type: Expression profiling by array.
Low-inflammatory lipid nanoparticle-based mRNA vaccine elicits protective immunity against H5N1 high-pathogenicity avian influenza virus with reduced adverse reactions (using dendritic cell of lymph n
GEO Series GSE279744. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Immunopathogenesis of lethal H5N1 avian influenza virus clade 2.3.4.4b infection in macaques
GEO Series GSE287709. Macaca fascicularis; Macaca mulatta. 65 samples. Type: Expression profiling by high throughput sequencing.
Disease severity is associated with differential gene expression at the early and late phases of infection in non-human primates infected with different H5N1 highly pathogenic avian influenza viruses
GEO Series GSE57970. Macaca mulatta. 45 samples. Type: Expression profiling by array.
HiSeq analysis of human gene expression profile following infection with highly pathogenic avian influenza A virus (H5N1; A/Chicken/Vietnam/0008/04)
GEO Series GSE119767. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Overexpression of chicken IRF7 increased viral replication and programmed cell death to the avian influenza virus infection through TGF-beta/FoxO signaling axis in DF-1
GEO Series GSE115131. Gallus gallus. 8 samples. Type: Expression profiling by high throughput sequencing.
Data from: Who is spreading avian influenza in the moving duck flock farming network of Indonesia?
Duck populations are considered to be a reservoir of Highly pathogenic avian influenza (HPAI) virus H5N1 in some agricultural production systems, as they are able to shed the virus for several days without clinical signs. Countries endemically affected with HPAI in Asia are characterised by production systems where ducks are fed on post-harvest spilled rice. During this scavenging process it is common for ducks to come into contact with other duck flocks or wild birds, thereby providing opportunities for virus spread. Effective risk management for HPAI has been significantly compromised by a limited understanding of management of moving duck flocks in these countries, despite of a small number of recent investigations. Here, for the first time, we described the management of moving duck flocks and the structure of the moving duck flock network in quantitative terms so that factors influencing the risk of HPAIV transmission can be identified. By following moving duck flock farmers over a period of 6 months in Java, Indonesia, we were able to describe the movement of flocks and to characterise the network of various types of actors associated with the production system. We used these data to estimate the basic reproductive number for HPAI virus spread. Our results suggest that focussing HPAI prevention measures on duck flocks alone will not be sufficient. Instead, the role of transporters of moving duck flocks, hatcheries and rice paddy owners, in the spread of the HPAI virus needs to be recognised.
Data from: Host interaction analysis of PA-N155 and PA-N182 in chicken cells reveals an essential role of UBA52 for replication of H5N1 avian influenza virus
PA-N155 and PA-N182 proteins were translated from the 11th and 13th start codon AUG of the RNA polymerase acidic protein (PA) mRNA of H5N1 influenza A virus (IAV), which plays an important role in viral replication. Little is known about the interactions between PA-N155 and PA-N182 and the host proteins. This study investigated the interaction landscape of PA-N155 and PA-N182 of H5N1 IAV in chicken cells while their interacting complexes were captured by immunoprecipitation and analyzed by mass spectrometry. A total of 491 (PA-N155) and 302 (PA-N182) interacting proteins were identified. Gene ontology and pathway enrichment analyses showed that proteins of the two interactomes were enriched in RNA processing, viral processing and protein transport, and proteins related to signaling pathways of proteasome, ribosome, and aminoacy1-tRNA biosynthesis were significantly enriched, suggesting their potential roles in H5N1 IAV infection. Comparative analysis of the interactome of PA, PA-N155, and PA-N182 identified UBA52 as a conserved host factor that interacted with all three viral proteins. UBA52 is a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein L40 at the C terminus. Knockdown of UBA52 significantly decreased the titer of H5N1 IAV in chicken cells and was accompanied with attenuated production of proinflammatory cytokines. Our analyses of the influenza–host protein interactomes identified UBA52 as a PA interaction protein for virus replication.
Studies of Avian Influenza Transmission to Humans in Egypt
ClinicalTrials.gov study NCT01150552. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Phase 1 Study to Evaluate the Immunogenicity and Safety of a Pandemic Avian Influenza Vaccine in Adults
ClinicalTrials.gov study NCT02335164. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Study of VGX-3400X, H5N1 Avian Influenza Virus DNA Plasmid + Electroporation in Healthy Adults
ClinicalTrials.gov study NCT01142362. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Immunogenicity and Safety of 2 Doses of Avian Influenza A (H5N1) Vaccine Administered 3 vs. 8 Weeks Apart
ClinicalTrials.gov study NCT07275060. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Avian Influenza Studies In Lebanon
ClinicalTrials.gov study NCT01107262. IPD Sharing: Not stated. Countries: 2. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.