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Dataset results
611 results for “Infertility”
Identifying Molecular Determinants of Infertility in Men (MODIFY)
ClinicalTrials.gov study NCT06147700. IPD Sharing: NO. Countries: 1. Publications: 10.
Correlation Between Serum Anti-Müllerian Hormone & Müllerian Ducts Anomalies in Infertility
ClinicalTrials.gov study NCT02436538. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Magnetic Resonance Imaging (MRI) Hysterosalpingography Versus Radiographic Hysterosalpingography in Female Infertility
ClinicalTrials.gov study NCT02108665. IPD Sharing: Not stated. Countries: 1. Publications: 0.
To Evaluate the Effect of Reveratrol,Folic Acid, Vitamin D, Vitamin B12 and B6 in Male Infertility
ClinicalTrials.gov study NCT03864198. IPD Sharing: NO. Countries: 1. Publications: 14.
Uterine Transplant in Absolute Uterine Infertility (AUIF)
ClinicalTrials.gov study NCT02741102. IPD Sharing: NO. Countries: 0. Publications: 10.
Color Doppler in Varicocelectomy in Infertile Patient
ClinicalTrials.gov study NCT03750370. IPD Sharing: Not stated. Countries: 1. Publications: 3.
A kaleidoscopic view of ovarian genes associated with infertility, subfertility and senescence
<p>Ovarian infertility and subfertility presenting with premature ovarian insufficiency (POI) and diminished ovarian reserve are major issues facing in the developed world due to the trend of delaying child birth. Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder affecting 6-10% of women in reproductive age. Based on advances in whole exome sequencing, evaluation of gene copy variants, together with family-based and genome-wide association studies (GWAS), we discussed genes responsible for the POI, PCOS, and ovarian senescence. We used a gene-centric approach to sort out literature deposited in the Ovarian Kaleidoscope database (http://okdb.appliedbioinfo.net) by sub-categorizing candidate genes as ligand-receptor signaling, meiosis and DNA repair, transcriptional factors, RNA metabolism, enzymes, and others. We discussed individual gene mutations found in POI patients and verification of gene functions in gene-deleted model organisms. Decreases in the expression of some of the POI genes could be responsible for early menopause, especially those essential for DNA repair and meiosis. Although multiple individual candidate gene single nucleotide polymorphisms have been analyzed in PCOS patients, only a limited number of findings have been verified and dealing with genes with known ovarian functions. We propose to set up a panel of candidate genes for targeted sequencing in POI patients and investigate ovarian expression of a set of candidate genes in PCOS patients, together with studies on mitochondria-associated genes in middle-aged subfertile patients. Continuing studies on POI and PCOS as well as ovarian senescence genes could allow better diagnosis and formulation of treatment strategies.</p>
Data from: Flexible polyandry in female flies is an adaptive response to infertile males
Infertility is common in nature despite its obvious cost to individual fitness. Rising global temperatures are predicted to decrease fertility, and male sterility is frequently used in attempts to regulate pest or disease vector populations. When males are infertile, females may mate with multiple males to ensure fertilisation, and changes in female mating behaviour in turn could intensify selection on male fertility. Fertility assurance is a potentially wide-spread explanation for polyandry, but whether and how it actually contributes to the evolution of polyandry is not clear. Moreover, whether a drop in male fertility would lead to a genetic increase in polyandry depends on whether females respond genetically or through behavioural plasticity to male infertility. Here, we experimentally manipulate male fertility through heat-exposure in Drosophila pseudoobscura, and test female discrimination against infertile males before and after mating. Using isogenic lines, we compare the roles of behaviourally plastic versus genetically fixed polyandry. We find that heat-exposed males are less active and attractive, and that females are more likely to remate after mating with these males. Remating rate increases with reduced reproductive output, indicating that females use current sperm storage threshold to make dynamic remating decisions. After remating with fertile males, females restore normal fecundity levels. Our results suggest that male infertility could explain the evolution of adaptively flexible polyandry, but is less likely to cause an increase in genetic polyandry.
Effect of Ejaculatory Abstinence on Semen Parameters in Male Factor Infertility Patients
ClinicalTrials.gov study NCT04206800. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Economic and Psychological Burden of Infertility Among Women Attending Women Health Hospital, Assiut University
ClinicalTrials.gov study NCT06664086. IPD Sharing: Not stated. Countries: 0. Publications: 2.
Liraglutide and Metformin Combination on Weight Loss, Metabolic - Endocrine Parameters and Pregnancy Rate in Women With PCOS, Obesity and Infertility
ClinicalTrials.gov study NCT05952882. IPD Sharing: Not stated. Countries: 0. Publications: 27.
Effectiveness and Safety of Bushen Culuan Decoction for Anovulatory Infertility
ClinicalTrials.gov study NCT03709849. IPD Sharing: UNDECIDED. Countries: 0. Publications: 1.
Psychiatric Disorders With Prolonged Infertility
ClinicalTrials.gov study NCT03569215. IPD Sharing: NO. Countries: 1. Publications: 0.
Effects of Infertility and Assisted Reproductive Technology on Sexual Function and Behavior
ClinicalTrials.gov study NCT07376109. IPD Sharing: NO. Countries: 1. Publications: 0.
Infections and Unexplained Infertility
ClinicalTrials.gov study NCT03581617. IPD Sharing: NO. Countries: 0. Publications: 1.
The Effects of Administration of Combined Docosahexaenoic Acid and Vitamin E Supplements on Spermatogram and Seminal Plasma Oxidative Stress in Infertile Men With Asthenozoospermia
ClinicalTrials.gov study NCT01846325. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Role of Nesfatin-1 and Nicotinamide in Infertile Women With Polycystic Ovary Syndrome
ClinicalTrials.gov study NCT03870035. IPD Sharing: Not stated. Countries: 0. Publications: 5.
Vitamin D Deficiency of Couples and Infertility
ClinicalTrials.gov study NCT03305510. IPD Sharing: UNDECIDED. Countries: 0. Publications: 1.
Retrospective Comparison of Pregnancy Outcome of Infertile Patients After Fresh and Warmed Single Blastocyst Transfer From 2014 to 2018.
ClinicalTrials.gov study NCT04310761. IPD Sharing: NO. Countries: 0. Publications: 4.
Royal Jelly Supplementation in Unexplained Male Infertility
ClinicalTrials.gov study NCT07337265. IPD Sharing: UNDECIDED. Countries: 0. Publications: 3.
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