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943
datasets available to search
ShareScore release 0.9.0
Dataset results
943 results for “Pancreas”
Management of Traumatic Pancreas Transection
ClinicalTrials.gov study NCT05856474. IPD Sharing: UNDECIDED. Countries: 1. Publications: 3.
The Norwegian Pancreas Transplantation (PTx) Study
ClinicalTrials.gov study NCT01957696. IPD Sharing: Not stated. Countries: 1. Publications: 22.
Screening for Early Pancreatic Neoplasia (Cancer of the Pancreas Screening or CAPS4 Study)
ClinicalTrials.gov study NCT00714701. IPD Sharing: YES. Countries: 1. Publications: 2.
Quebec Pancreas Cancer Study
ClinicalTrials.gov study NCT04104230. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Study Assessing the Effect of Transpapillary Pancreas Duct Stent in Resection of the Pancreatic Tail
ClinicalTrials.gov study NCT00500968. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Cancer of the Head of the Pancreas: Early Surgery or Preoperative Biliary Drainage?
ClinicalTrials.gov study NCT03358095. IPD Sharing: NO. Countries: 1. Publications: 2.
Hybrid Artificial Pancreas in Home Setting
ClinicalTrials.gov study NCT02153190. IPD Sharing: Not stated. Countries: 3. Publications: 2.
Chemotherapy in Treating Patients With Locally Advanced or Metastatic Cancer of the Pancreas or Bile Duct
ClinicalTrials.gov study NCT00010088. IPD Sharing: Not stated. Countries: 2. Publications: 2.
Gemcitabine and Radiation Therapy in Treating Patients With Cancer of the Pancreas
ClinicalTrials.gov study NCT00010166. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effect of Heatwaves on Glycemic Control in People With Type 1 Diabetes Treated With Artificial Pancreas
ClinicalTrials.gov study NCT06214780. IPD Sharing: NO. Countries: 1. Publications: 4.
Stereotactic Body Radiotherapy and Focal Adhesion Kinase Inhibitor in Advanced Pancreas Adenocarcinoma
ClinicalTrials.gov study NCT04331041. IPD Sharing: YES. Countries: 1. Publications: 1.
Tissue Pharmacokinetics of Intraoperative Gemcitabine in Resectable Adenocarcinoma of the Pancreas
ClinicalTrials.gov study NCT01276613. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Phase II MULTICENTRE Trial of Needle Based Laser Confocal Endomicroscopy of Cystic and Solid Tumours of the Pancreas
ClinicalTrials.gov study NCT02523170. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Feasibility Study of a Portable Artificial Pancreas System in Type 1 Diabetes Mellitus (T1DM) - Padova
ClinicalTrials.gov study NCT01447992. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Phase I Trial of Gemcitabine and Radiation in Locally Advanced Unresectable Cancer of the Pancreas
ClinicalTrials.gov study NCT00001431. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Fluorouracil, Gemcitabine, and Radiation Therapy in Treating Patients With Cancer of the Pancreas
ClinicalTrials.gov study NCT00003216. IPD Sharing: Not stated. Countries: 2. Publications: 10.
Long Term Outcomes After EUS-guided Ablation for Cystic Tumors of the Pancreas
ClinicalTrials.gov study NCT00689715. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Clinical Evaluation Of Needle-based Confocal Laser Endomicroscopy in The Lymph Nodes Along With Masses and Cystic Tumors of the Pancreas
ClinicalTrials.gov study NCT01563133. IPD Sharing: Not stated. Countries: 1. Publications: 21.
Data from: Transcriptomic analysis of the lesser spotted catshark (Scyliorhinus canicula) pancreas, liver and brain reveals molecular level conservation of vertebrate pancreas function
Background: Understanding the evolution of the vertebrate pancreas is key to understanding its functions. The chondrichthyes (cartilaginous fish such as sharks and rays) have often been suggested to possess the most ancient example of a distinct pancreas with both hormonal (endocrine) and digestive (exocrine) roles. The lack of genetic, genomic and transcriptomic data for cartilaginous fish has hindered a more thorough understanding of the molecular-level functions of the chondrichthyan pancreas, particularly with respect to their "unusual" energy metabolism (where ketone bodies and amino acids are the main oxidative fuel source) and their paradoxical ability to both maintain stable blood glucose levels and tolerate extensive periods of hypoglycemia. In order to shed light on some of these processes, we carried out the first large-scale comparative transcriptomic survey of multiple cartilaginous fish tissues: the pancreas, brain and liver of the lesser spotted catshark, Scyliorhinus canicula. Results: We generated a mutli-tissue assembly comprising 86,006 contigs, of which 44,794 were assigned to a particular tissue or combination of tissues based on mapping of sequencing reads. We have characterised transcripts encoding genes involved in insulin regulation, glucose sensing, transcriptional regulation, signaling and digestion, as well as many peptide hormone precursors and their receptors for the first time. Comparisons to mammalian pancreas transcriptomes reveals that mechanisms of glucose sensing and insulin regulation used to establish and maintain a stable internal environment are conserved across jawed vertebrates and likely pre-date the vertebrate radiation. Conservation of pancreatic hormones and genes encoding digestive proteins support the single, early evolution of a distinct pancreatic gland with endocrine and exocrine functions in jawed vertebrates. In addition, we demonstrate that chondrichthyes lack pancreatic polypeptide (PP) and that reports of PP in the literature are likely due cross-reaction with PYY and/or NPY in the pancreas. A three hormone islet organ is therefore the ancestral jawed vertebrate condition, later elaborated upon only in the tetrapod lineage. Conclusions: The cartilaginous fish are a great untapped resource for the reconstruction of patterns and processes of vertebrate evolution and new approaches such as those described in this paper will greatly facilitate their incorporation into the rank of "model organism".
Data from: Mapping and validation of a major QTL affecting resistance to pancreas disease (salmonid alphavirus) in Atlantic salmon (Salmo salar)
Pancreas disease (PD), caused by a salmonid alphavirus (SAV), has a large negative economic and animal welfare impact on Atlantic salmon aquaculture. Evidence for genetic variation in host resistance to this disease has been reported, suggesting that selective breeding may potentially form an important component of disease control. The aim of this study was to explore the genetic architecture of resistance to PD, using survival data collected from two unrelated populations of Atlantic salmon; one challenged with SAV as fry in freshwater (POP 1) and one challenged with SAV as post-smolts in sea water (POP 2). Analyses of the binary survival data revealed a moderate-to-high heritability for host resistance to PD in both populations (fry POP 1 h2~0.5; post-smolt POP 2 h2~0.4). Subsets of both populations were genotyped for single nucleotide polymorphism markers, and six putative resistance quantitative trait loci (QTL) were identified. One of these QTL was mapped to the same location on chromosome 3 in both populations, reaching chromosome-wide significance in both the sire- and dam-based analyses in POP 1, and genome-wide significance in a combined analysis in POP 2. This independently verified QTL explains a significant proportion of host genetic variation in resistance to PD in both populations, suggesting a common underlying mechanism for genetic resistance across lifecycle stages. Markers associated with this QTL are being incorporated into selective breeding programs to improve PD resistance.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.