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1,035
datasets available to search
ShareScore release 0.9.0
Dataset results
1,035 results for “cancer invasion”
Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery
ClinicalTrials.gov study NCT06731998. IPD Sharing: NO. Countries: 1. Publications: 11.
Sacituzumab Govitecan, Preceding Radical Cystectomy, in Treating Patients With Muscle-invasive Bladder Cancer
ClinicalTrials.gov study NCT05226117. IPD Sharing: NO. Countries: 1. Publications: 0.
Tamoxifen, Ovarian Ablation, and/or Combination Chemotherapy in Treating Premenopausal Women With Stage I, Stage II, or Stage IIIA Invasive Breast Cancer
ClinicalTrials.gov study NCT00002580. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Evaluation of Non-Invasive Assays for the Detection of Urothelial Cancer
ClinicalTrials.gov study NCT00872495. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Trans-Pacific Multicenter Collaborative Study of Minimally Invasive Proximal Versus Total Gastrectomy for Proximal Gastric and Gastroesophageal Junction Cancers
ClinicalTrials.gov study NCT05205343. IPD Sharing: Not stated. Countries: 3. Publications: 2.
A First-in-Human Study of alpha1H in Patients With Non-muscle Invasive Bladder Cancer
ClinicalTrials.gov study NCT03560479. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Assessment of Efficacy and Safety of Durvalumab Plus BCG Compared to the Standard Therapy With BCG in Non-muscle Invasive Bladder Cancer
ClinicalTrials.gov study NCT03528694. IPD Sharing: YES. Countries: 12. Publications: 1.
Thulium Laser En-bloc Resection of Primary Non-muscle Invasive Bladder Cancer
ClinicalTrials.gov study NCT06818799. IPD Sharing: NO. Countries: 1. Publications: 1.
Safety, Feasibility and Effect of an Individualized Physical Activity Intervention for Gastric Cancer Patient Undergoing Minimally Invasive Gastrectomy: a Pilot Study
ClinicalTrials.gov study NCT01751880. IPD Sharing: Not stated. Countries: 1. Publications: 1.
The Difference of Two Year Recurrence Rate According to Anesthetic Method During Transurethral Resection of Bladder Mass in Patients With Non-muscle Invasive Bladder Cancer: Prospective, Randomized, C
ClinicalTrials.gov study NCT03597087. IPD Sharing: NO. Countries: 1. Publications: 24.
Invasive Treatment of Pain Associated With Pancreatic Cancer on Different Levels of WHO Analgesic Ladder
ClinicalTrials.gov study NCT02424279. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Mycobacterial Cell Wall-DNA Complex in Treatment of BCG-refractory Patients With Non-muscle Invasive Bladder Cancer
ClinicalTrials.gov study NCT00406068. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Clinical Evaluation of Vagal Nerve Preservation in Minimally Invasive Surgery for Early Lung Cancer
ClinicalTrials.gov study NCT04125979. IPD Sharing: NO. Countries: 1. Publications: 4.
A Clinical Trial Aimed At Assessing the Efficacy and Safety of VT-101 for the Treatment of Non-muscle Invasive Bladder Cancer
ClinicalTrials.gov study NCT06632964. IPD Sharing: NO. Countries: 1. Publications: 9.
Minimal Invasive Strategies for Good and Complete Response to Chemoradiation in Rectal Cancer
ClinicalTrials.gov study NCT00939666. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer
ClinicalTrials.gov study NCT03244384. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Circulating myeloid-derived suppressor cells facilitate invasion of thyroid cancer cells by repressing miR-486-3p
Open the record for dataset details and reuse information.
Data from: CRISPR-Cas9 mediated CD133 knockout inhibits colon cancer invasion through reduced epithelial-mesenchymal transition
Open the record for dataset details and reuse information.
Data from: Prognostic value of ki67 in BCG-treated non-muscle invasive bladder cancer: a meta-analysis and systematic review
Objectives: The aim of this study was to explore the prognostic value of ki67 as a marker in non-muscle-invasive bladder cancer (NMIBC) patients treated with Bacillus Calmette–Guérin (BCG). Methods: Studies were systematically retrieved from the relevant databases (Web of Science, PubMed, Cochrane Library, and Embase), and the expiry date was May 2017. The research steps referred to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis statement. Results: A total of 11 studies that complied with the inclusion criteria were enrolled. The expression of ki67 was not statistically significantly associated with recurrence-free survival (RFS) [hazard ratio (HR): 1.331; 95% CI: 0.980–1.809)]. No significant heterogeneity was found among all included studies (I2 = 36.7%, P = 0.148). The expression of ki67 was statistically significantly associated with progression-free survival (PFS) (HR: 2.567; 95% CI: 1.562–4.219), and the overexpression of ki67 was the risk factor for PFS. Significant heterogeneity was noted among all the included studies (I2 = 55.6%, P = 0.021). The studies that might cause heterogeneity were excluded using the Galbraith plot, and then the meta-analysis was performed again. The results showed that the expression of ki67 was still associated with PFS (HR: 2.922; 95% CI: 2.002–4.266). Conclusions: The overexpression of ki67 was the risk factor for PFS, and the relationship between the expression of ki67 and RFS was not statistically significant in patients with NMIBC treated with BCG intravesical immunotherapy. Well-designed, prospective, randomized controlled trials with a large sample size are still needed to validate the findings.
Data from: High-throughput adaptive sampling for whole-slide histopathology image analysis (HASHI) via convolutional neural networks: application to invasive breast cancer detection
Precise detection of invasive cancer on whole-slide images (WSI) is a critical first step in digital pathology tasks of diagnosis and grading. Convolutional neural network (CNN) is the most popular representation learning method for computer vision tasks, which have been successfully applied in digital pathology, including tumor and mitosis detection. However, CNNs are typically only tenable with relatively small image sizes (200x200 pixels). Only recently, Fully convolutional networks (FCN) are able to deal with larger image sizes (500x500 pixels) for semantic segmentation. Hence, the direct application of CNNs to WSI is not computationally feasible because for a WSI, a CNN would require billions or trillions of parameters. To alleviate this issue, this paper presents a novel method, High-throughput Adaptive Sampling for whole-slide Histopathology Image analysis (HASHI), which involves: i) a new efficient adaptive sampling method based on probability gradient and quasi-Monte Carlo sampling, and, ii) a powerful representation learning classifier based on CNNs. We applied HASHI to automated detection of invasive breast cancer on WSI. HASHI was trained and validated using three different data cohorts involving near 500 cases and then independently tested on 195 studies from The Cancer Genome Atlas. The results show that (1) the adaptive sampling method is an effective strategy to deal with WSI without compromising prediction accuracy by obtaining comparative results of a dense sampling (~6 million of samples in 24 hours) with far fewer samples (~2,000 samples in 1 minute), and (2) on an independent test dataset, HASHI is effective and robust to data from multiple sites, scanners, and platforms, achieving an average Dice coefficient of 76%.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.