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204
datasets available to search
ShareScore release 0.9.0
Dataset results
204 results for “chronic migraine”
Non-steroidal Anti-inflammatory Drugs Alone or With a Triptan and Reports of Transition From Episodic to Chronic Migraine
ClinicalTrials.gov study NCT01435941. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Open Label Study of BOTOX® (Botulinum Toxin Type A) as Headache Prophylaxis in Chinese Patients With Chronic Migraine
ClinicalTrials.gov study NCT03193359. IPD Sharing: Not stated. Countries: 0. Publications: 0.
BOTOX® (Botulinum Toxin Type A) as Headache Prophylaxis in Chinese Participants With Chronic Migraine
ClinicalTrials.gov study NCT03193346. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Treatment of Cervical Pain in Chronic Migraine
ClinicalTrials.gov study NCT03453203. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Middle Meningeal Artery Embolization for Chronic Migraine
ClinicalTrials.gov study NCT07044648. IPD Sharing: NO. Countries: 0. Publications: 0.
Occipital Nerve Stimulation in Chronic Migraine
ClinicalTrials.gov study NCT07087678. IPD Sharing: YES. Countries: 0. Publications: 0.
The Effectiveness and Safety of Topiramate on Prevention of Chronic Migraine
ClinicalTrials.gov study NCT00216606. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Developing a Mobile Health Pain-Coping Skills Training Program for the Treatment of Chronic Migraine: AIM 4
ClinicalTrials.gov study NCT03465826. IPD Sharing: NO. Countries: 0. Publications: 0.
A Study to Evaluate Botulinum Toxin Type A for Injection（HengLi®）for Prophylactic Treatment of Chronic Migraine
ClinicalTrials.gov study NCT02291380. IPD Sharing: NO. Countries: 0. Publications: 0.
Study of Wireless Nerve Stimulation in the Treatment of Chronic Migraine
ClinicalTrials.gov study NCT02725554. IPD Sharing: YES. Countries: 0. Publications: 0.
Effects of Transcranial Direct Current Stimulation in Refractory Chronic Migraine and Medication-overuse Headache
ClinicalTrials.gov study NCT01752439. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Dataset related to article " Effect of a Mindfulness-Based Intervention for Chronic Migraine and High Frequency Episodic Migraine in Adolescents: A Pilot Single-Arm Open-Label Study"
<p><strong>Data related to the longitudinal single-arm open study on the effect of mindfulness in adolescents with CM and HFEM</strong></p> <p> </p> <p> </p> <p> </p> <p> </p>
Dataset related to article "WITHDRAWAL FAILURE IN PATIENTS WITH CHRONIC MIGRAINE AND MEDICATION OVERUSE HEADACHE"
<p>The file contains baseline and follow-up data (SPSS FILES .sav) referred to the MOH-COST study, used for a secondary analysis </p>
Identified important EEG channels using recurrent analysis in patients with chronic migraine
<p>This database contains calculated indicators of channel significance based on the application of recurrent analysis to EEG data using the example of the article Runnova A, Selskii A, Emelyanova E, Zhuravlev M, Popova M, Kiselev A, Shamionov R. Modification of Joint Recurrence Quantification Analysis ( JRQA) for assessing individual characteristics from short EEG time series. Chaos. 2021;31(9):093116. doi: 10.1063/5.0055550. For each EEG channel of each subject, the channel significance indicator was separately calculated for all presentations of stimuli in the cognitive test, which are located in the SR folder. The RR_Simple_Hard folder contains the results of calculating significant channels separately for simple presentations - 3 and 4 squares, and complex presentations - 7 and 8 squares. A description of the EEG setup, subjects, and experimental design is provided below.</p><p>Test subjects volunteered to participate in the experiment. The biomedical data were processed honoring the confidentiality and anonymity of the study respondents. All procedures in studies involving human participants were conducted in accordance with the principles of the Declaration of Helsinki and approved by the Research Ethics Committee at Saratov State Medical University. Written informed consent was given by all participants. The participants were diagnosed in compliance with the diagnostic criteria of the International Classification of Headache Disorders (ICHD-3, beta version). We used the migraine questionnaire to evaluate the data on migraine attacks and disease courses. The exclusion criteria were acute headache, other neurological disorders, and intake of medicines targeting the central nervous system (including medications for migraine prophylaxis) within the preceding 24 h, as well as a Beck Depression Inventory (BDI) score >12 points. The sample comprised 23 subjects.</p><p>The study group included patients with chronic and recurrent migraine. The subjects had no other serious health problems, or drug or alcohol addictions. Patients were 27–66 years of age.</p><p>During all experiments, the multichannel EEG data were recorded using the EEG recorder Encephalan-EEGR-19/26 (Medicom MTD, Taganrog, Russian Federation). The data were recorded at a sampling rate of 500 Hz using the conventional monopolar recording technique with two reference electrodes and multiple recording electrodes (n = 31). EEG signals were obtained using special headcaps with prewired Ag/AgCl adhesive electrodes. Two reference electrodes, A1 and A2, were located on the mastoid processes, and the ground electrode (N) was placed above the forehead. EEG signals were filtered using a bandpass filter with cutoff frequencies of 0.5 Hz (high pass filter) and 30 Hz (low pass filter), and a notch filter of 50 Hz. The experiments were carried out in the early afternoon hours at a specially equipped laboratory. During monitoring, the subjects were in a comfortable reclining position in a neurophysiological chair with support for the neck and the back of the head in order to avoid the occurrence of artifacts associated with muscle tension in these areas. The neuropsychological experiment allowed for distinguishing cognitive ERPs. At the beginning and end of the experiment, passive wakefulness was recorded for 10 min each time. In between, the active part of the experiment was recorded for ~40 min. During the active part, short presentations of visual stimuli were delivered in a pseudorandom sequence. For all subjects, the order of stimulus presentation, duration of stimulus presentation, and duration of pauses between stimuli were identical. Each subject observed 350 stimuli. The stimulus was presented for 0.4–0.8 s. After its presentation, during a pause until the next stimulus, the subject saw solely a gray screen. Each visual stimulus per se was an image with a different number of squares (3–8). The task of the subject was to estimate an even or odd number of squares and make a choice by pressing one of two buttons on the remote control.</p>
Facial expressions modulate pain perception in patients with chronic migraine
<p>This is the processed data for the manuscript "Matamala-Gomez Marta, Bottiroli ara, Sances Grazia, Allena Marta, De Icco Roverto, Ghiotto Natascia, Guaschino Elena, Sandrini Giorgio, and Tassorelli Cristina (2022) Facia Expressions modulate pain perception in patients with chronic migraine. Cephalalgia. doi: 10.1177/03331024221075081".</p> <p>Dataset refers to the effects of the exposure to different visual feedback conditions on pain perception<br> in patients with chronic migraine. It is a 1X4 within-subject study design, in which 38 female chronic migraine patients were exposed to different visual stimuli – positive face, neutral face, negative face, and control (white screen) – during a migraine attack. Visual stimuli were presented 3 times in a randomized order (each condition lasted 40 seconds). Migraine pain ratings and identification<br> scores were assessed immediately after the observation of each visual condition.</p>
Anodal transcranial direct current stimulation in chronic migraine and medication overuse headache: A pilot double-blind randomized sham-controlled trial
<p>This dataset includes raw data from the article “Anodal transcranial direct current stimulation in chronic migraine and medication overuse headache: A pilot double-blind randomized sham-controlled trial”.</p> <p>In this study, we enrolled 20 patients with chronic migraine (CM) and medication overuse headache (MOH). They were hospitalized for a 7-day detoxification treatment and were randomly assigned to anodal tDCS or sham stimulation delivered over the primary motor cortex contralateral to the prevalent migraine pain side every day for 5 days. Clinical data were recorded at baseline (T0), after 1 month (T2) and 6 months (T3). EEG recording was performed at T0, at the end of the tDCS/Sham treatment, and at T2.</p> <p>At T2 and T3, we found a significant reduction in monthly migraine days (p = 0.001), which were more pronounced in the tDCS group when compared to the sham group (p = 0.016). At T2, we found a significant increase of alpha rhythm in occipital leads, which was significantly higher in tDCS group when compared to sham group. In conclusion, tDCS showed adjuvant effects to detoxification in the management of patients with CM and MOH. The EEG recording showed a significant potentiation of alpha rhythm, which may represent a correlate of the underlying changes in cortico-thalamic connections.</p>
Peripheral changes of endocannabinoid system components in episodic and chronic migraine patients: A pilot study
<p>This dataset includes raw data of the paper “Peripheral changes of endocannabinoid system components in episodic and chronic migraine patients: A pilot study”. In this paper, the gene expression of endocannabinoid system components was assayed in peripheral blood mononuclear cells of 25 subjects with episodic migraine, 26 subjects with chronic migraine with medication overuse (CM-MO) and 24 age-matched healthy controls.</p> <p>The protein expression of cannabinoid receptors 1 and 2 as well as DNA methylation changes in genes involved in endocannabinoid system components were also evaluated. Both episodic migraine and CM-MO subjects showed higher cannabinoid receptor 1 and cannabinoid receptor 2 gene and protein expression compared to controls. Fatty acid amide hydrolase gene expression, involved in ananda-mide degradation, was lower in migraine groups compared to healthy control subjects. N-arachidonoyl phosphatidyl-ethanolamine phospholipase D gene expression was significantly higher in all migraineurs, as were monoacylglycerollipase and diacylglycerol lipase gene expressions. The above markers significantly correlated with the number of migraine days and with the days of acute drug intake.</p> <p>The findings point to transcriptional changes in endocannabinoid system components occurring in migraineurs and suggest these peripheral changes could be amenable for a wider adoption to further investigate their role and applicability in the clinical field.</p>
Alexithymia and psychological distress in fibromyalgia and chronic migraine: a cross-sectional study
<p>This is the processed data for the manuscript "Alexithymia and psychological distress in fibromyalgia and chronic migraine: a cross-sectional study".</p> <p>Dataset refers the prevalence of psychological distress and alexithymia in patients with fibromyalgia and chronic migraine, compared to a healthy control group.</p> <p>To this end, participants were assessed using the Toronto Alexithymia Scale and Hospital Anxiety and Depression Scale. Results suggest a common psychological dysregulation in patients suffering from fibromyalgia and chronic migraine, which manifests with a different degree of intensity and into a different expression of physical symptoms.</p>
Dataset related to Article "A SINGLE-GROUP STUDY ON THE EFFECT OF ONABOTULINUMTOXINA IN PATIENTS WITH CHRONIC MIGRAINE ASSOCIATED TO MEDICATION OVERUSE HEADACHE: PAIN CATASTROPHIZING PLAYS A ROLE"_ submitted
<p>THIS DATASET INCLUDES INFORMATION ON HEADACHE FREQUENCY, MEDICATION INTAKE, MIDAS SCORE, AVERAGE PAIN, HIT-6, ASC-12 AND PCS REFERRED TO PATIENTS RECEIVING ONABOTULINUMTOXINA AS PROPHYLAXIS FOR CM-MOH OVER 12 MONTHS.</p>
Potential contribution of hypertension to evolution of chronic migraine and related mechanisms
<p>Patients with migraine with or without aura were enrolled and were divided into two groups based on headache frequency: high frequency migraineurs (H) (≥10 days per month) and low frequency migraineurs (<10 days per month) (L). Within each group, hypertensive (H) and non-hypertensive (N) patients were selected on the basis either of hypertension history or of the result of 24-hour blood pressure monitoring in agreement with 2018 ESC/ESH Guidelines [26].</p> <p>The cerebral vascular reactivity was studied monitoring the blood flow velocity in the medial cerebral artery (MCA) of both sides using two pulsed wave Doppler probes (2 MHz) positioned at the temporal acoustic windows with continuous blood pressure monitoring and recorded with a signal integrator (Poewer Lab).</p> <p>All patients were free of medications known to interfere with the vascular ton.</p> <p>The acquisition was carried out in a dim light room with the patient in supine position. After 10 minutes of basal recording, nitroglycerine (NTG, 0.9 mg) was administered sublingually and monitoring was carried out for a further 30 minutes. Afterwards, in off-line mode, samplings of about 20 cycles every 2 minutes were considered to determine the mean velocity at baseline, while samplings of about 40 cycles were carried out at 10, 20 and 30 minutes after drug administration. Possible artifacts were excluded from samplings.</p> <p>Tilting test was carried out with a tilting bed that allowed to continuously measure blood pressure and heart rate at different degrees of inclination. In our laboratory, the patients were evaluated first in clinostatism for 10 minutes and then at an inclination of 60 degrees for a further 10 minutes. The aim of the test was to assess the activities of the sympathetic and parasympathetic nervous system, expressed as a percentage, and the sympathetic-vagal balance.</p> <p>Twenty-four hours blood pressure monitoring was carried out with an automatic recorder equipped with an armlet that was applied to the non-dominant arm and that takes measurements every 15 minutes during the day and every 30 minutes during the night. This allowed to assess the circadian rhythm of pressure and, in particular, the dipping, i.e. the reduction of the pressure during sleep.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.